The London Research Institute research groups are based at Lincoln’s Inn Fields and Clare Hall. Our major research themes are: the biology of tumours and tissues, cellular regulatory mechanisms and genomic integrity and cell cycle.
Genomic Integrity and Cell Cycle
The theme of genomic Integrity and cell cycle encompasses the following research fields:
- Chromosome biology
- Checkpoint controls
- Cell Cycle
- DNA replication and chromosome dynamics
- DNA damage and repair
Group leaders involved in these research areas are listed below:
Simon Boulton
: DNA Damage Response
Peter Cherepanov
: Chromatin Structure and Mobile DNA
Julie Cooper
: Telomere Biology
Alessandro Costa
: Architecture and Dynamics of Macromolecular Machines
Vincenzo Costanzo
: DNA Damage and Genomic Stability
John Diffley
: Chromosome Replication
Peter Karran
: Mammalian DNA Repair
Paul Nurse / Jacqueline Hayles
: Cell Cycle
Mark Petronczki
: Cell Division and Aneuploidy
Martin Singleton
: Macromolecular Structure and Function
Thomas Surrey
: Microtubule Cytoskeleton
Jesper Svejstrup
: Mechanisms of Gene Transcription
Takashi Toda
: Cell Regulation
Frank Uhlmann
: Chromosome Segregation
Helle Ulrich
: DNA Damage Tolerance
Stephen West
: Genetic Recombination
