Cancer Research UK

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The London Research Institute research groups are based at Lincoln’s Inn Fields and Clare Hall. Our major research themes are: the biology of tumours and tissues, cellular regulatory mechanisms and genomic integrity and cell cycle.

John Fox : Advanced Computation

The purpose of the Advanced Computation Laboratory, led by John Fox,  was to carry out research in formal computer science and its applications in biomedicine, focusing on artificial intelligence and cognitive systems, as the basis for developing innovative information technologies to support patient care.

The lab’s work focused on the theory and application of cognitive systems to biomedical problems. They sought to maintain a ‘virtuous circle’ from basic research in formal computational science to clinical applications. Basic research provided a secure foundation for the design of innovative technologies, which in turn were used to develop clinical applications. The loop was closed by clinical evaluation and experimental testing of applications, which then fed objective data back into theory assessment.

John Left the LRI to become a Professor of Engineering Science at Oxford University.

Current Website

Significant LRI Papers
  • Beveridge M, Fox JAutomatic generation of spoken dialogue from medical plans. Journal of Biomedical Informatics. 2006;39:482-499 (Abstract)
  • Jeffreys BR, Kelley LA, Sergot M, Fox J, Sternberg M. Capturing expert knowledge with argumentation: a case study in bioinformatics. Bioinformatics. 2006;22(8):924-33 (Abstract)
  • Fox, J, Glasspool D, Modgil S. A canonical agent model for healthcare applications. IEEE Intelligent Systems. 2006;21:21-28 (Abstract)
  • Fox, J, Alabassi A, Patkar V, Rose T, Black E. An ontological approach to modelling tasks and goals. Comput Biol Med. 2006;36(7-8):837-56 (Abstract)