The London Research Institute research groups are based at Lincoln’s Inn Fields and Clare Hall. Our major research themes are: the biology of tumours and tissues, cellular regulatory mechanisms and genomic integrity and cell cycle.
Stephen West : Genetic Recombination
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The Genetic Recombination laboratory at Cancer Research UK is situated at Clare Hall in Hertfordshire. As part of CR-UK's London Research Institute, Clare Hall primarily specialises in basic research into mechanisms of DNA replication, recombination, repair and cell cycle. Studies such as these are critical for our understanding of the relationships between genome instability and tumourigenesis.
Steve received a PhD in biochemistry from Newcastle University, before joining the Department of Therapeutic Radiology at Yale University, where he was a post-doc with Paul Howard-Flanders. He moved to the UK in 1985 to set up a laboratory at the Imperial Cancer Research Fund (now Cancer Research UK) where he is Senior Group Leader and Deputy Director of Clare Hall Laboratories. Steve was elected as a Fellow of the Royal Society in 1995, to the Academy of Medical Sciences in 2000, to the European Academy of Cancer Sciences in 2011, and as a Member of EMBO in 1994. Steve's scientific contributions have been acknowledged by several prize awards, including the Swiss Bridge Prize Award for Cancer Research in 2001 and 2009, the Louis-Jeantet Prize for Medicine in 2007, and the Novartis medal & prize from the Biochemical Society in 2008. In 2012 he will be the recipient of the Genetics Society Medal. In 2002 Steve received the Leeuwenheek medal and prize from the Royal Society, and in 2010 presented the Royal Society GlaxoSmithKline Prize Lecture. In 2010 he also received a prestigious ERC Senior Investigator Award that will provide additional support to his lab for the next 5 years.
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