The London Research Institute publishes in numerous international journals and various in-house publications, such as the Annual LRI Scientific Report.
Papers
Researchers at the London Research Institute publish their research throughout the year in leading academic journals. The latest papers and archived articles are available below.
The LRI also produces an annual report, which highlights the achievements of the past year.
Highlighted Paper:
Thaunat O, Granja AG, Barral P, Filby A, Montaner B, Collinson L, Martinez-Martin N, Harwood NE, Bruckbauer A, Batista FD. (2012) Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity. Science 335:475-9 (Abstract) (Facundo Batista)
B cell activation results in the generation of antibodies and the establishment of immunological memory that together provide protection against viruses, bacteria and also cancers.[read more...]
Selected New Papers
Blackford AN, Schwab RA, Nieminuszczy J, Deans AJ, West SC, Niedzwiedz W. The DNA translocase activity of FANCM protects stalled replication forks. Hum Mol Genet. 2012 Jan 24. [Epub ahead of print]
(Abstract)
(Stephen West)
Modi BG, Neustadter J, Binda E, Lewis J, Filler RB, Roberts SJ, Kwong BY, Reddy S, Overton JD, Galan A, Tigelaar R, Cai L, Fu P, Shlomchik M, Kaplan DH, Hayday A, Girardi M. Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma. Science. 2012 Jan 6;335(6064):104-8.
(Abstract)
(Adrian Hayday)
Okamoto SY, Sato M, Toda T, Yamamoto M. SCF Ensures Meiotic Chromosome Segregation Through a Resolution of Meiotic Recombination Intermediates. PLoS One. 2012;7(1):e30622. Epub 2012 Jan 23.
(Abstract)
(Takashi Toda)
Perriches T, Singleton MR. The structure of the yeast kinetochore Ndc10 DNA-binding domain reveals an unexpected evolutionary relationship to tyrosine recombinases. J Biol Chem. 2012 Jan 3. [Epub ahead of print]
(Abstract)
(Martin Singleton)
Thaunat O, Granja AG, Barral P, Filby A, Montaner B, Collinson L, Martinez-Martin N, Harwood NE, Bruckbauer A, Batista FD. Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity. Science. 2012 Jan 27;335(6067):475-9.
(Abstract)
(Facundo Batista)
Wade A, Thomas C, Kalmar B, Terenzio M, Garin J, Greensmith L, Schiavo G. Activated Leukocyte Cell Adhesion Molecule (Alcam) Modulates Neurotrophin Signaling. J Neurochem. 2012 Jan 13. doi: 10.1111/j.1471-4159.2012.07658.x. [Epub ahead of print]
(Abstract)
(Giampietro Schiavo)
Greenwood J, Cooper JP. Non-coding telomeric and subtelomeric transcripts are differentially regulated by telomeric and heterochromatin assembly factors in fission yeast. Nucleic Acids Res. 2011 Dec 1. [Epub ahead of print]
(Abstract)
(Julie Cooper)
Hashimoto Y, Puddu F, Costanzo V. RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks. Nat Struct Mol Biol. 2011 Dec 4. doi: 10.1038/nsmb.2177. [Epub ahead of print]
(Abstract)
(Vincenzo Costanzo)
Ikebe C, Konishi M, Hirata D, Matsusaka T, Toda T. Systematic Localization Study on Novel Proteins Encoded by Meiotically Up-Regulated ORFs in Fission Yeast. Biosci Biotechnol Biochem. 2011 Dec 7. [Epub ahead of print]
(Abstract)
(Takashi Toda)
Shafi S, Vantourout P, Wallace G, Antoun A, Vaughan R, Stanford M, Hayday A. An NKG2D-Mediated Human Lymphoid Stress Surveillance Response with High Interindividual Variation. Sci Transl Med. 2011 Dec 14;3(113):113ra124. Epub 2011 Nov 30.
(Abstract)
(Adrian Hayday)
