The London Research Institute publishes in numerous international journals and various in-house publications, such as the Annual LRI Scientific Report.
Papers
Researchers at the London Research Institute publish their research throughout the year in leading academic journals. The latest papers and archived articles are available below.
The LRI also produces an annual report, which highlights the achievements of the past year.
Highlighted Paper:
Davies CC, Chakraborty A, Diefenbacher ME, Skehel M, Behrens A. Arginine methylation of the c-Jun coactivator RACO-1 is required for c-Jun/AP-1 activation. EMBO J. 2013 [Abstract].
RACO-1 methylation is required for c-Jun/AP-1 activation.
Tumour development requires many changes in cells to enable them to grow and divide uncontrollably, and one of the master regulators that can coordinate these changes is the transcription factor c-Jun/AP-1. [read more]
Selected New Papers
Burrell RA, McClelland SE, Endesfelder D, Groth P, Weller M-C, Shaikh N, Domingo E, Kanu N, Dewhurst SM, Gronroos E, Chew SK, Rowan AJ, Schenk A, Sheffer M, Howell M, Kschischo M, Behrens A, Helleday T, Bartek J, Tomlinson IP, Swanton C. Replication stress links cancer structural and numerical chromosomalinstability. Nature. 2013; 494(7438): 492-6
(Abstract)
(Axel Behrens)
Chatterjee A, Zakian S, Hu XW, Singleton MR. Structural insights into cohesion establishment by Wpl1. EMBO J. 2013;32:677-687.
(Abstract)
(Martin Singleton)
Kjær S, Linch M, Purkiss A, Kostelecky B, Knowles PP, Rosse C, Riou P, Soudy C, Kaye S, Patel B, Soriano E, Murray-Rust J, Barton C Dillon C, Roffey J, Parker PJ & McDonald NQ. Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isozymes. Biochemical Journal 2013; 451:329-342.
(Abstract)
(Neil McDonald)
Tang, N.H., Takada, H., Hsu, K.S., and Toda, T. The internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment. Mol Biol Cell. 2013;24(8):1122-33
(Abstract)
(Takashi Toda)
Burrell RA, McClelland SE, Endesfelder D, Groth P, Weller MC, Shaikh N, Domingo E, Kanu N, Dewhurst SM, Gronroos E, Chew SK, Rowan AJ, Schenk A, Sheffer M, Howell M, Kschischo M, Behrens A, Helleday T, Bartek J, Tomlinson IP, Swanton C,. Replication stress links structural and numerical cancer chromosomal instability. Nature. 2013;494(7438):492-6.
(Abstract)
(Charles Swanton)
Sidor CM, Brain R, Thompson BJ. Mask proteins are cofactors of Yorkie/YAP in the Hippo pathway. Current Biology. 2013;23(3):223-8
(Abstract)
(Barry Thompson)
Chapman JR, Barral P, Vannier J-B, Borel-V, Steger M, Tomas-Loba A, Sartori AA, Adams I, Batista FD, Boulton SJ (2013). RIF1 is essential for 53BP1-dependent non-homologous end joining and suppression of DNA double strand break resection. Molecular Cell, 49: 858-71.
(Abstract)
(Simon Boulton)
Lopez-Serra L, Lengronne A, Borges V, Kelly G, Uhlmann F. Budding yeast wapl controls sister chromatid cohesion maintenance and chromosome condensation. Curr Biol. 2013; 7;23(1):64-9
(Abstract)
(Frank Uhlmann)
Tomita K, Bez C, Fennell A, Cooper JP. A single internal telomere tract ensures meiotic spindle formation. EMBO Rep. 2013;14(3):252-60
(Abstract)
(Julie Cooper)
Wehr, M.C., Holder, M.V., Gailite, I., Saunders, R.E., Maile, T.M., Ciirdaeva, E., Instrell, R., Jiang, M., Howell, M., Rossner, M.J., and Tapon, N. (2013). Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila. Nat Cell Biol 15, 61-71.
(Abstract)
(Nic Tapon)
